h2g2 The Hitchhiker's Guide to the Galaxy: Earth Edition

OK ... more suggestions:

"sitting at a computer reading h2g2" = "sitting at a computer reading h2g2."

"were living on this Planet" = "were living on this planet"

[Footnote 1]: "cells without cell nucleus are called prokaryotic" = "cells without a cell nucleus are called prokaryotic cells"

"a bacterium reproduces itself by" = "a bacterium reproduces by"

"In addition to that, bacteria can also exchange genetic information with other bacteria,2, this allowed mutations which increase an individual bacterium's chance of survival becoming widespread, so bacteria can evolve to become drug resistant" = "In addition to that, bacteria can also exchange genetic information with other bacteria[2], allowing mutations which increase an individual bacterium's chance of survival and becoming widespread. This allows bacteria to [link]evolve[link] to become [link]drug resistant[link]."

"Most bacteria are completely harmless, most surfaces, including your skin are covered by them." = "Most bacteria are completely harmless - most surfaces, including your skin, are covered by them."

"This particle, before it is has" = "This particle, before it has"

"A virus cannot live on its own, in order to replicate it has to attach itself to one of your cells and hijacks the protein making equipment." = "A virus cannot live on its own - in order to replicate it has to attach itself to one of your cells and hijack its protein making equipment."

"Usually a virus killes" = "Usually a virus kills"

* Remove "- Sneaky"

"All Viruses attack cells, most virus attack a specic type of cell, though some are more versitle than others, for instance the HIV virus often, but not always attacks T cells, part of your immune system." = "All viruses attack cells but most viruses attack a specic type of cell. Some are more versitle than others - the [link]HIV[link] virus, for example, often, but not always, attacks T cells (part of your immune system)."

"Others known as Bacteriophages" = "Others known as [link]bacteriophages[link]"

"In this entry bacteria and viruses are referred to as pathogens4 each pathogen has antigens, which are specific feature, usually a protein on it's surface, which the immune system responds to, these features are called antigens.." = "In this entry bacteria and viruses are referred to as pathogens[4]. Each pathogen has antigens, which are specific features such as a protein on its surface. The immune system responds to these proteins."

"in such an effcient way" = "in such an efficient way"

"for a persistant pathogen" = "for a persistent pathogen"

"Many can be found in food, most can be killed if you cook your food thoroughly but some will be on your hand when you eat it, or on your plate or knife and fork." = "Many can be found in food although most can be killed if you cook your food thoroughly. Some will be on your hand when you eat it, on your plate and on your knife and fork."

"pathogens might collonise" = "pathogens might colonise"

"This happens in the lung" = "This happens in the lungs"

"This activates Mast cells, which release chemicals which increase your chances of fighting disease." = "This activates Mast cells, which release chemicals that increase your chances of fighting disease."

"Eosionphil" = "Eosinophil"

"other phagocytic cells3." = "other phagocytic cells."

"There are two main mechanisms to activate the complement proteins," = "There are two main mechanisms to activate the complement proteins:"

"your bone marrow produces massive amounts" = "your bone marrow produces large numbers"

"A number of singalling chemicals" = "A number of signalling chemicals"

"Some of these chemicals signals" = "Some of these chemical signals"

"a few times - (20 or so) and then" = "a few times - about 20 - and then"

"Once a neutrophil has started to die, then it will send" = "Once a neutrophil has started to die, it will send"

"it displays at its surface" = "it displays on its surface"

"Most of the stuff is recycled" = "Most of the chemicals are recycled"

"can't recycle them fast enough, that's when we get an abscess." = "can't recycle them fast enough, which is why we get an abscess."

"however neutrophils can't get in" = "however neutrophils also can't get in"

"Some bacteria such as the ones that cause Tuberculosis and Leprosy manage" = "Some bacteria, such as the ones that cause Tuberculosis and Leprosy, manage"

"and the bacteria has successfully been killed" = "and the bacteria has been killed"

"then it hijacks your cells protein-producing" = "then hijack your cells' protein-producing"

"We produce antibodies against viruses as described above, they attach to the part of the viruses that is used to get into cells." = "We produce antibodies against viruses as described above. They attach to the part of the viruses that is used to get into cells."


RhoMuNuQ {Waving around the fine tooth comb }

again, I've got as far as sneaky (which I think I'll leave it, for some reason it was the sentance I imagined when I started writing the article)...

I've got to go to the gym now! well not got to but I seem to have some motivation to do some excersize and that doesn't happen very often!

OK ... no problem!

If you want to leave "Sneaky", maybe it could become a subheader?

RhoMuNuQ

i think the sneaky is fine where it is

i have no more big nits to pick - you did a pretty good cleanup job this time and all that's left for you to do is to get rid of the spelling mistakes! - only a couple of minor suggestions, if you'd like to put them in.

1. re: route of entry and the like - the whole gastrointestinal tract is covered with a mucosal layer, and your pathogens are likely to encounter them before they get to the stomach.

2. the macrophage is just as professional as the neutrophil, and equally important, and therefore (i think) deserves credit for swallowing bacteria as well (of course, how efficient they are depends on whether they're activated or not, and what bacteria they just gobbled, but don't put that in, i think)

3. you may want to re-introduce the complement system at the start of your complement section, so as to give the reader an idea of what you are going to discuss before embarking on your discussion. (since you put a function intro for the rest, it's only fair that you do the same for the complement!) something short, like maybe "the Complement System is a set of proteins that, when activated, attract phagocytes to the site of infection and promote bacteria-killing. they are made up of a number of proteins (10 or so), all of which are designated C(for complement) followed by a number."

4. re: sneaky bacteria escaping - you may want to add that not only can some bacteria escape killing by phagocytes (which you've already said), some actually *exploit* the macrophage as a convenient transport to other areas of the body this way. (once they have inactivated the killing mechanism, the mac becomes a comfortable little cubby hole where they can breed unchecked, no longer having to fear the hostile outside - and a taxi to deliver them to new sites for infection. i find that *so* nifty)

and finally...

5. inactivated does not = killed. some vaccines are made with attenuated pathogens (like the sabin vaccine); some others are made with dead ones (the original salk vaccine). the reason is that sometimes it does not pay to have living organisms in your vaccine, no matter how inactivated! (the reason i mentioned polio vaccines is because in recent years the new cases of polio were actually caused by the oral - sabin - vaccine intended to protect the victims)

anyway, good work. i hope to see it in the edited guide soon!

Phew all done!

it's kinda like performing a frenetic 6-hour rain dance, huh?

Yes! do you think someone would kindly pick this please!!..I would but that would be highly immorral.

Your Guide Entry has just been picked from Peer Review by one of our Scouts, and is now heading off into the Editorial Process, which ends with publication in the Edited Guide. We've therefore moved this Review Conversation out of Peer Review and to the entry itself.

If you'd like to know what happens now, check out the page on 'What Happens after your Entry has been Recommended?' at EditedGuide-Process. We hope this explains everything.

Thanks for contributing to the Edited Guide!

Well done Z!

RhoMuNuQ

RhoMuNuQ.. thanks for all your help..

Not only immoral but also illegal. You cannot recommend your own entry.

Not to worry though, it has been done.

Congratulations – See you on the front page.

Stuart

I know.. thanks to whoever did reccomend it...

No problem, Z!

RhoMuNuQ

but you're not a Scout... anyway...

Oops ... I was replying to your post where you thanked me for my help!

RhoMuNuQ

(I wasn't under the delusion that I picked it )

RhoMuNuQ

congrats! i'll put a link in my page to it once the new add is up!

Sorry that I didn't continue writing, but I was severly occupied by work and the like. When I managed to check back, a lot has already changed (to the better, of course) and the article was already off into editorial process...

So, apologies and congratulations!
FJ

No need to apologise and thanks for the congratulations!!!!