h2g2 The Hitchhiker's Guide to the Galaxy: Earth Edition

Kumasi is Ghana's second city (Ashanti people might suggest its first). There's a good bus service from Accra, but this is a place to stay in rather than a day trip. Come to think of it, I'm not sure that day trips are a great idea in Ghana- most places to stay are cheap for Westerners, and even cheaper outside Accra; and in a hot country it's good not to hurry.
Kumasi is a great centre in itself. Visit the Cultural Centre (less hassly than the one in Accra), the market (is it the biggest in Africa?- it's enormous, and sells everything from odd bits of animals to a made-to-measure dress (ready tomorrow, another reason to stay)), the Asantehene's Palace (palace of the King of Ashanti, interesting mixture of cultures), and the Kumasi Fort (where a few years back someone opened a locked door and found a stash of chief's regalia confiscated in around 1900 by the British after they had been shut up in the fort by a rebellion lead by a woman).