The following is an example of a pyramid block settling table for six selections which finished at 2/1, 3/1, 4/1, 6/1, 9/1 and 14/1
The SINGLES column is generated directly from the prices as per the rules for basic factors in A1148096 - Settling Complicated Bets with a calculator
Each column is then generated by adding up all of the figures in the previous column ABOVE the new entry, and multiplying by the entry in the SINGLES column for that row. So the second entry in the TREBLES column is calculated as 12 + 35 = 47, 47 x 7 = 329.
Total up each column to read off the returns to a £1.00 unit stake, for each component of the particular multiple/perm bet.
You can check your work by adding up all of the totals. This should come to the same total as calculating a full cover bet using the additional point rule, as defined in Settling complicated bets with a calculator. In this case 4 x 5 x 6 x 8 x 11 x 16 = 168960, 168960 - 1 = 168959, which just happens to be the correct total.
Hint: The maths is easier (and far quicker on a calculator) if you leave the more irrational odds at the bottom of the table (I.e. keep all of you X/1 odds at the top, then put in any X/2's and put all the annoying stuff like 8/13 at the bottom)1