h2g2 The Hitchhiker's Guide to the Galaxy: Earth Edition

Life imitates art frequently with The West Wing.

RL: Mark McKinnon quits McCain camp after Obama becomes nominee. (May 20, 2008)
WW: Leon Montero, a Hispanic Vinick advisor, quits Vinick camp once Santos is the nominee. (Season 7)

RL: Drivers licenses for illegal immigrants issue in New York, divides Democrats. Senator Clinton opposes giving drivers licenses to illegal immigrants, Senator Obama supports. (early 2008)
WW: Drivers licenses for illegal immigrants issue in California, divides Democrats. Vice President Russell opposes giving drivers licenses to illegal immigrants, Congressman Santos supports. ("La Palabra", Season 6, episode 128, aired 3/9/2005)

RL: President Bush drives bike into police officer in Scotland. (July, 2005) He also fell off his bike in May, 2004 and fell off a Segway scooter in June, 2003.
WW: President Bartlett drives bike into a chestnut tree. ("Pilot", Season 1, episode 1, aired 9/22/1999)

RL: Republicans nominate a moderate white-haired old Senator from a western state (McCain, from Arizona), while Democrats nominate a young minority candidate with an attractive wife and two children (Obama). (2008)
WW: Republicans nominate a moderate white-haired old Senator from a western state (Vinick, from California), while Democrats nominate a young minority candidate with an attractive wife and two children (Santos). (Seasons 6 and 7, running from 2004-2006) (apparently Santos was inspired by Obama, well before he decided to run for the Presidency - see http://www.guardian.co.uk/world/2008/feb/21/barackobama.uselections2008)

RL: Republicans wrap up nominating contest by Super Tuesday, while Democrats squabble and argue for months. (2008)
WW: Republicans wrap up nominating contest by Super Tuesday, while Democrats squabble and argue for months. (Season 6, running from late 2004 through early 2005)

RL: President Bush's daughter Jenna is married during his second term in the "Western White House" in Crawford, Texas. (May 10, 2008)
WW: President Bartlett's daughter Ellie is married during his second term in the White House. ("The Wedding", Season 7, episode 141, aired 12/11/2005)

WW: When Leo asks Josh to go see Jed Bartlett speak for the first time he says, "The Democrats aren't going to nominate another liberal, academic, former Governor from New England. I mean, we're dumb, but we're not that dumb." ("In the Shadow of Two Gunmen", Season 2, episode 23, aired 10/4/2000)
RL: Democrats nominated another liberal, academic New Englander in 2004.

I haven't watched any later WW for a while, so the similarities have never struck me, but now you mention it, it's quite obvious. Thanks for that, very interesting!