h2g2 The Hitchhiker's Guide to the Galaxy: Earth Edition

Typically people use maps to get to Columbus, but that is really no necessary. The key landmark to look for when seeking Columbus is the "orange barrel." This rare and mystic creature has over run the whole area of central ohio. Many experts agree that if you see one of these orange barrels, you need simply to pursue it. Given enough time, it will lead you to the mass of its people, which is in Columbus.

Alternately, just keep sniffing the air 'till you catch a whiff of the Olentangy (Old 'n' Tangy) River, then drive towards the stench.

just look for a building that looks like a knock off of the empire state building

I'll assume you're referencing the LeVeque Tower, which was actually completed 4 years BEFORE the Empire State Building. Since they only vaguely resemble each other, I'll also assume that the Empire State didn't copy the LeVeque. They are both excellent examples of Art Deco skyscrapers though. It is interesting to note that the LeVeque was the tallest building between Chicago and New York for many years and was used as a reference point for early aviators. Apology accepted.